Disturbances of lung function in HIV positive patients

Authors

DOI:

https://doi.org/10.59471/ijhsc2022120

Keywords:

HIV, Chronic obstructive pulmonary disease (COPD), Antiretroviral treatment

Abstract

The presence of disturbances in the respiratory function on HIV positive patients, derive from multiple causes. The principal mechanism of injury is the inflammation that triggers a flood of biomarkers, which leads to a respiratory function decline. Within the causes, we find modifiable factors such as tobacco and drugs use, and non-modifiable factors like gender, age, CD4 recount, viral burden, HIV itself, ART, co-infections such us HCV and the presence of breathing infections like Pneumocystis Jiroveci pneumonia and Tuberculosis. Facing a chronic pathology requires to control obstructive alterations so, it results convenient to request spirometry and diffusion tests.

Downloads

Download data is not yet available.

References

ONUSIDA. UNAIDS. http://www.unaids.org/es.

Boletín sobre: VIH- SIDA en la Argentina. N 33. Ministerio de la Nación. 2018

Lupo S, Welker G, Agostini M, Lupo S. (2018). Chronic pulmonary disease in HIV-positive patients with preserved immunity Rev. Méd. Rosario 84: 11-16.

Fitzpatrick, M. E., Kunisaki, K. M., & Morris, A. (2018). Pulmonary disease in HIV-infected adults in the era of antiretroviral therapy. Aids, 32(3), 277-292.

Ronit A, Lundgren J, Afzal S, et al. (2018) Airflow limitation in people living with HIV and matched uninfected controls. Thorax Published Online. doi: 10.1136/thoraxjnl-2017-211079.

Agostini M, Marconi L, Trapé L, Torrano JM, Bustamante L. (2018). Emphysema in HIV positive patient: diagnostic and therapeutic Conduct. J HIV Retrovirus. Vol 4. N 2.9.

Lambert AA, Crothers K. (2018). Abnormal Lung Function in HIV-infected Adults: An Under-Recognized Risk Factor for Early Mortality Ann;15(2):160-162.

Triplette, M., Justice, A., Attia, E. F., Tate, J., Brown, S. T., Goetz, M. B, Crothers, K. (2018) Markers of chronic obstructive pulmonary disease are associated with mortality in people living with HIV. AIDS;32(4):487–493.

MacDonald, D. M., Zanotto, A. D., Collins, G., Baker, J. V., Czarnecki, M., Loiza, E., & Kunisaki, K. M. (2019). Associations between baseline biomarkers and lung function in HIV-positive individuals. AIDS:33(4), 655-664.

North C, Kakuhikire B, Tsai A, Tracy R, Hunt P, Kwon D, Christiani D, Okello S, Siedner J. (2018). Brief Report: Systemic Inflammation, Immune Activation, and Impaired Lung Function Among People Living with HIV in Rural Uganda. JAIDS;78(5), 543-548.

Chandra, D, Gupta, A., Fitzpatrick, M., Haberlen, S. A., Neupane, M., Leader, J. K. & Sciurba, F.(2019). Lung function, coronary artery disease, and mortality in HIV. Annals of the American Thoracic Society: 16(6), 687-697.

Crothers C, Harding B, Whitney B, Delaney J, Nance R, Heckbert S, Budoff M, Mathews WC, Eron J. Moore R, Mugavero M, Saag M, Kitahata M, CraneH. (2019). COPD and myocardial infring risk by type in people living with HIV. 16th Conference on Retrovirus and Opportunistic Infection (CROI). Seattle, March 04-07, 2019.

Kunisaki KM. Lung function in men whih and whihout HIV. AIDS 2020;34:1227-1235. http://doi.org/10.1097/QAD.0000000000002526.

Sabin CA, Kunisaki KM, Bagkeris E, Post FA, Sachikonye M, Boffito M, Anderson J, Mallon P, Williams I, Vera JH, Johnson M, Babalis D, Winston A. Respiratory symptoms and chronic bronchitis in people with and without HIV infection. HIV Med. 2021;22(1):11-21. http://doi.org/10.1111/hiv.12955.

Thudium et al. (2021). Faster lung function decline in well-treated people living with HIV compared with uninfected controls: a longitudinal matched cohort stydy. 18th European AIDS Conference, London, abstract 052/2, 2021.

Agostini, M. Alteración de la función respiratoria relacionada al VIH. Tesis Doctoral en Medicina. Universidad Nacional Nacional, Rosario; 2022.

Bigna JJ, Kenne AM, Asangbeh SL, Sibetcheu AT. Prevalence of chronic obstructive pulmonary disease in the global population with HIV: a systematic review and meta-analysis. Lancet Glob Health. 2018;6(2):e193-e202. http://doi.org/10.1016/S2214-109X(17)30451-5.

Makinson A, Hayot M, Eymard-Duvernay S, Ribet C, Raffi F, Pialoux G, Zucman D, Poizot-Martin I, Bonnet F, Abgrall S, Tattevin P, Cheret A, Ferry T, Mauboussin JM, Marchand L, Rouzaud C, Reynes J, Zins M, Le Moing V; ANRS EP48 HIV CHEST study Team. HIV is associated with airway obstruction: a matched controlled study. AIDS. 2018;32(2):227-232. http://doi.org/10.1097/QAD.0000000000001691.

Mishra, NC, Aakriti M. Prevalence of Chronic Lung Disease in HIV Patients. EC Pulmonology and Respiratory Medicine. 2019;8:372-373.

Agostini M. COPD in HIV Infected Patients. Clin HIV AIDS J. 2018;1:103.

Downloads

Published

2022-12-02

How to Cite

1.
Marcela A. Disturbances of lung function in HIV positive patients. Interam. J. Health Sci. [Internet]. 2022 Dec. 2 [cited 2023 Jun. 9];(2):120. Available from: https://ijhsc.com/journal/article/view/120

Issue

Section

Review Article

Categories